How do antidepressants treat nerve pain?

May 9th, 2022

LabOnline, Other, 04/05/2022
Australian researchers have revealed how tricyclic antidepressants (TCAs) work against nerve pain, paving the way for further research and new therapies to treat the debilitating condition. Their results have been published in the journal RSC Medicinal Chemistry. […] Now a multidisciplinary team of researchers from CSIRO, The University of Queensland’s Institute for Molecular Bioscience and Monash University have used a neuroblastoma cell line to demonstrate exactly how 11 TCAs and two closely related drugs worked to block pain, and identified which ones were most effective.

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